We are a systems neuroscience laboratory studying how the brain generates, learns, and recovers motor skills. Movement is the brain's ultimate output - the way cognitive, perceptual, and reflexive processes are expressed in the world. Our research seeks to understand how motor circuits are organized in the healthy brain, how sleep consolidates the skills we practice during the day, and how these processes break down and can be rebuilt after stroke.
A central theme of our work is that stroke recovery is fundamentally a re-learning problem. The same neural machinery the brain uses to acquire a new skill - coordinated activity between the motor cortex and cerebellum, refined overnight during sleep - must be reactivated and retrained after injury. By mapping these mechanisms in animal models and measuring their signatures in human stroke patients, we aim to develop targeted, brain-state-aware stimulation strategies that harness the brain's own recovery processes to improve rehabilitation outcomes.
Principal Investigator:
Tanuj Gulati, PhD (Cedars Bio | UCLA Profile)
Cedars-Sinai / UCLA
Affiliations:
Cedars-Sinai Health Sciences University:
Center for Neural Science and Medicine
Department of Biomedical Sciences
Cedars-Sinai PhD Program in Biomedical Sciences
UCLA:
David Geffen School of Medicine, UCLA
Bioengineering, Samueli School of Engineering, UCLA
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